CytoProcessor® - Annette's Case n°11

CytoProcessor’s AI for Digital Cytology aids in the screening of atrophic cases.

As a Cytotechnologist or Cyto-Pathologist, atrophic cases, primarily due to natural degeneration of the parabasal cells in a background of fibrin, are big challenges and brainteasers while you screen for Cervical Cancer.

Degenerated parabasal cells, cellular debris, old blood and pollution of the samples by lubricants/ultrasound gels can lead to overdiagnosing as degenerated and/or bad stained parabasal cells can mimic HSIL / carcinoma cells. A smaller number of cells and stripped nuclei are further difficulty in analyzing atrophic samples.

Furthermore, carcinoma cells may also be misdiagnosed as normal atrophic cells!

Lubricants and ultrasound gels, which can affect staining quality and cell quantity on slides, should be avoided prior to sampling, a fact of which gynecologists must be aware.

CytoProcessor aids in making reliable diagnoses by distinguishing and sorting the most diagnostically relevant cells. 1  2

On a medical grade screen it’s easier to assess normal (degenerated) cells and its nuclear details, and therefore better to distinguish degenerated atrophic cells from the small, atypical cells.

To effectively distinguish these cells, the following criteria are indispensable for diagnosing atrophic and atypical cells 3:
– Scroll to see the criteria on the information grid

— Annette W. Hamminga (CTIAC), Digital Cytology Expert at Datexim

¹ See our clinical study: CytoProcessor® : A New Cervical Cancer Screening System for Remote Diagnosis - Datexim
² See our scientific publications: Scientific publications - Datexim
³ See the information grid: THE BETHESDA SYSTEM

CytoProcessor® is a CE marked IVD device, intended for use by healthcare professionals only. Please consult the user guide provided by the manufacturer, DATEXIM, for detailed conditions of use and recommendations for safe and effective operation.